Allantoin is a metabolic intermediate in most organisms, which is produced from the oxidation of uric acid. Well known is the occurrence of allantoin in the roots and leaves of the comfrey plant. The comfrey extract has a long history to promote wound healing and skin soothing. Allantoin can also be synthesized and is identical to the naturally occurring Allantoin. 

Allantoin is a skin protectant with anti-irritant properties and skin nourishing benefits. It promotes the renewal of the skin by enhancing desquamation and removing dead skin cells, which helps in softening of the skin. It aids in wound healing and cell proliferation and reduces skin irritation. This active ingredient is widely used in cosmetic and pharmaceutical applications in the form of creams, lotions, lip products, shaving creams, suntan products and baby products and is suitable for sensitive skin. It can also be used in various oral products such as toothpaste and mouthwash. Allantoin complies with CTFA and JSCI requirements.